Saxenda Weight Loss: Effects, Side Effects, & How to Use

Are you interested in losing weight with the injectable medication Saxenda (liraglutide)? This article provides a thorough explanation of the expected weight loss effects, potential side effects, treatment costs, and proper usage of Saxenda. We also compare it with Ozempic and discuss what to do if you’re not seeing results. Check it out now!

What is Saxenda (Liraglutide)? Basics as a Weight Loss Medication

Saxenda is a medication used for chronic weight management in adults who are overweight or obese and have at least one weight-related comorbidity. Its active ingredient is liraglutide, which is a GLP-1 receptor agonist. Originally developed and approved for the treatment of type 2 diabetes, liraglutide was later found to be effective in promoting weight loss, leading to its approval as a dedicated weight loss medication under the brand name Saxenda in many countries, including Japan. It is administered as a daily subcutaneous injection. Unlike diet supplements or over-the-counter products, Saxenda is a prescription medication that requires a doctor’s diagnosis and guidance.

Mechanism of Weight Loss with Saxenda and Expected Effects

Saxenda helps people lose weight by acting on appetite-regulating centers in the brain and slowing down gastric emptying. This leads to reduced calorie intake and, consequently, weight loss.

Action of the GLP-1 Analog Saxenda

Liraglutide, the active ingredient in Saxenda, mimics the action of a naturally occurring hormone called glucagon-like peptide-1 (GLP-1). GLP-1 is produced in the intestines in response to food intake. Its effects relevant to weight loss include:

• Increasing feelings of fullness and satiety: GLP-1 acts on the brain’s appetite centers (such as the hypothalamus) to signal that you are full, reducing hunger and the desire to eat.
• Slowing gastric emptying: It slows down how quickly food leaves your stomach. This helps you feel full for longer after eating and reduces the likelihood of overeating.
• Lowering blood sugar levels: While not the primary mechanism for weight loss in non-diabetic individuals, GLP-1 also stimulates insulin secretion and suppresses glucagon secretion in a glucose-dependent manner. This effect is more prominent in individuals with type 2 diabetes.

By mimicking these natural effects of GLP-1, Saxenda helps to reduce appetite and calorie intake, supporting weight loss efforts.

Clinical Trial Data and Weight Loss Rate with Saxenda

Clinical trials have demonstrated the effectiveness of Saxenda for weight management. In a large-scale study (SCALE Obesity and Prediabetes trial), patients treated with Saxenda achieved significant weight loss compared to those receiving a placebo, both in conjunction with lifestyle interventions (diet and exercise).

• Average Weight Loss: Patients treated with Saxenda 3.0 mg daily achieved an average weight loss of about 8-10% of their initial body weight over a period of approximately one year. Those on placebo typically lost around 2-3%.
• Percentage of Patients Achieving Significant Weight Loss: A higher percentage of patients on Saxenda achieved a weight loss of 5% or more, and 10% or more, compared to the placebo group. For example, around 60-65% of patients on Saxenda lost 5% or more of their body weight, while only about 20-25% on placebo did. Achieving a 5% weight loss is clinically significant and can improve various health markers.

It is important to note that these are average results from clinical trials. Individual weight loss may vary depending on factors such as adherence to treatment, lifestyle changes (diet and exercise), initial weight, and underlying health conditions. Saxenda is most effective when used as an adjunct to a reduced-calorie diet and increased physical activity.

Cases Where Saxenda Treatment is Recommended

Saxenda is generally recommended for adults who meet specific criteria related to body weight and health status. In Japan, Saxenda (Victoza) has been approved for diabetes, but Saxenda specifically for obesity was approved in 2023. The typical criteria for considering Saxenda for weight loss include:

• Body Mass Index (BMI): Usually a BMI of 30 kg/m² or greater (obese) or a BMI of 27 kg/m² or greater (overweight) with at least one weight-related comorbidity.
• Weight-Related Comorbidities: These can include type 2 diabetes, high blood pressure (hypertension), high cholesterol (dyslipidemia), or obstructive sleep apnea.
• Failure of Previous Attempts: Individuals who have struggled to achieve and maintain significant weight loss through diet and exercise alone may be candidates.
• Readiness to Commit: Patients should be willing to make lifestyle changes alongside medication use.

A thorough medical evaluation by a healthcare professional is necessary to determine if Saxenda is appropriate for an individual, considering their medical history, current health status, and other medications.

What is the Weight Loss Pace and Duration with Saxenda?

The pace and duration of weight loss with Saxenda vary from person to person. It is not a rapid weight loss solution but rather a tool to support gradual, sustainable weight loss.

How Much Weight Can Be Lost in a Month with Saxenda?

While individual results differ significantly, some people may start to see noticeable changes within the first month of treatment. During the initial phase, as the dose is gradually increased, side effects like nausea may occur, potentially affecting food intake and leading to some early weight loss. However, a realistic expectation for the first month is often modest, perhaps around 1-3% of initial body weight. Clinical trials show that weight loss continues over several months, with the most significant loss typically occurring within the first 6-12 months. Focusing on sustainable lifestyle changes alongside medication is key, rather than fixating on rapid monthly drops.

When Does the Effect Start to Be Felt?

Some individuals report feeling reduced appetite or increased fullness within a few days of starting Saxenda, especially as the dose is titrated upwards. However, the significant weight loss effect usually becomes apparent over several weeks or months as the cumulative effect of reduced calorie intake takes hold. Consistency in daily injections and adherence to diet and exercise recommendations are crucial for experiencing the full benefits. Patience is important, as it takes time for the body to adjust and for weight loss to occur.

Long-Term Weight Loss Effects and Maintenance

The goal of Saxenda treatment is not only to achieve weight loss but also to maintain it long-term. Clinical trials have shown that patients who continue using Saxenda maintain their weight loss better than those who stop. Long-term use (e.g., beyond one year) may be necessary for some individuals to prevent weight regain. The duration of treatment should be determined by a healthcare professional based on the individual’s response, tolerance, and overall health goals. Weight management is often a chronic condition, and sustained lifestyle changes, potentially supported by medication, are essential for long-term success.

Main Side Effects of Saxenda and How to Manage Them

Like all medications, Saxenda can cause side effects. Most are mild to moderate and tend to decrease over time as the body adjusts to the medication.

Commonly Reported Side Effects (Nausea, Stomach Pain, etc.)

The most common side effects of Saxenda are gastrointestinal and include:

• Nausea: This is the most frequently reported side effect, especially during the initial dose escalation phase. It often improves over time.
• Diarrhea or Constipation: Changes in bowel habits are common.
• Vomiting: Less common than nausea but can occur.
• Abdominal Pain: Discomfort in the stomach area.
• Indigestion: Feeling full or bloated.

Other common side effects can include:

• Headache: May occur, especially early in treatment.
• Fatigue: Feeling tired.
• Injection site reactions: Redness, itching, or swelling at the injection site.

To manage nausea and other gastrointestinal side effects:

• Eat smaller, more frequent meals.
• Avoid fatty or heavy foods.
• Eat slowly.
• Drink clear liquids.
• Avoid lying down immediately after eating.
• Ensure adequate hydration.

If side effects are bothersome or persistent, consult your doctor. They may recommend adjusting the dose or offering strategies to manage the symptoms.

Potential for Serious Side Effects

Although rare, Saxenda can potentially cause more serious side effects. It’s important to be aware of these and seek immediate medical attention if they occur.

• Pancreatitis: Inflammation of the pancreas. Symptoms include severe abdominal pain (often radiating to the back), nausea, and vomiting.
• Gallbladder Problems: Gallstones (cholelithiasis) or inflammation of the gallbladder (cholecystitis). Symptoms include pain in the upper abdomen, fever, and jaundice (yellowing of skin or eyes). Weight loss itself can also increase the risk of gallstones.
• Increased Heart Rate: Some patients may experience a slight increase in heart rate.
• Kidney Problems: Worsening kidney function or kidney failure, especially in individuals who experience severe vomiting or diarrhea leading to dehydration.
• Serious Allergic Reactions: Symptoms like rash, swelling of the face, lips, tongue, or throat, difficulty breathing, or fainting require immediate medical attention.
• Risk of Thyroid C-Cell Tumors: Based on animal studies, there is a potential risk of thyroid C-cell tumors, including medullary thyroid carcinoma (MTC). Saxenda is contraindicated in patients with a personal or family history of MTC or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). While the risk in humans is unknown, any neck mass, difficulty swallowing, hoarseness, or shortness of breath should be reported to your doctor.

If you experience any symptoms that concern you, especially severe abdominal pain, persistent vomiting, or signs of allergic reaction, contact your doctor immediately.

Tips for Reducing Side Effects

Several strategies can help minimize the side effects of Saxenda:

• Follow the Dose Escalation Schedule: Gradually increasing the dose as prescribed by your doctor (step-up) allows your body to adjust to the medication and can significantly reduce the severity of side effects, especially nausea. Do not increase the dose faster than recommended.
• Adjust Eating Habits: As mentioned, eating smaller, less fatty meals can help manage gastrointestinal upset.
• Stay Hydrated: Drinking plenty of water is essential, particularly if experiencing diarrhea or vomiting.
• Proper Injection Technique: Using the correct technique and rotating injection sites can help reduce injection site reactions.
• Communicate with Your Doctor: If side effects are bothersome or persistent, discuss them with your healthcare provider. They can provide advice, adjust the dose, or consider other options if necessary. Do not stop the medication or change the dose without consulting your doctor.

Saxenda vs. Ozempic: Comparing Weight Loss Medications

Saxenda (liraglutide) and Ozempic (semaglutide) are both GLP-1 receptor agonists used for weight management (though Ozempic is also primarily for type 2 diabetes, with higher doses marketed as Wegovy for obesity). They share similarities but also have key differences, particularly regarding administration frequency, weight loss efficacy, and cost.

Feature	Saxenda (Liraglutide)	Ozempic (Semaglutide)
Primary Use	Chronic Weight Management (approved for obesity)	Type 2 Diabetes (approved for obesity at higher doses – Wegovy)
Active Ingredient	Liraglutide	Semaglutide
Approval for Obesity	Yes (Saxenda)	Yes (Wegovy – higher dose of semaglutide)
Administration	Daily subcutaneous injection	Weekly subcutaneous injection
Typical Dose Range	0.6 mg to 3.0 mg daily	0.25 mg to 2.0 mg weekly (Ozempic for diabetes)
Weight Loss Effect	Average ~8-10% of body weight in clinical trials	Average ~15-17% of body weight reported in clinical trials with Wegovy
Side Effect Profile	Similar gastrointestinal side effects (nausea, etc.), generally mild	Similar gastrointestinal side effects, can be more pronounced due to weekly dose
Convenience	Requires daily injection	Requires weekly injection (more convenient for some)
Cost (Self-Pay)	High (varies by clinic/pharmacy), no insurance for obesity in Japan	High (varies by clinic/pharmacy), no insurance for obesity in Japan
Insurance (Japan)	Not covered for weight loss treatment	Covered for Type 2 Diabetes treatment (not for weight loss)

Comparison of Weight Loss Efficacy

Clinical trials suggest that semaglutide (Ozempic/Wegovy) generally leads to greater weight loss than liraglutide (Saxenda). The STEP trials for semaglutide for obesity reported average weight loss in the range of 15-17% of initial body weight, compared to the 8-10% seen with Saxenda in the SCALE trials. This difference in efficacy is a key point when considering treatment options, though individual responses can vary.

Comparison of Side Effect Profiles

Both medications share similar gastrointestinal side effects, such as nausea, vomiting, diarrhea, and constipation. These are related to their GLP-1 action on the digestive system. While the types of side effects are similar, the incidence and severity can differ. Because semaglutide is given weekly, the peak concentration in the body is higher than with daily liraglutide, which could potentially lead to more pronounced side effects for some individuals, although tolerance often builds over time with both medications.

Usage and Administration Frequency

A major difference is the frequency of administration. Saxenda requires a daily injection, whereas Ozempic and Wegovy require only a weekly injection. For patients who find daily injections bothersome, a weekly option like semaglutide may be more appealing and easier to adhere to. However, some patients prefer the daily option as it allows for more flexible dose adjustments in response to side effects.

Insurance Coverage and Cost Differences

In Japan, like many other countries, the use of Saxenda specifically for weight loss in non-diabetic individuals is not covered by health insurance and is considered a self-pay (cash-pay) treatment. The cost can be substantial, depending on the clinic and the dose used. Ozempic is approved in Japan for type 2 diabetes and is covered by insurance for this purpose. However, if used off-label for weight loss in individuals without diabetes, it would also be a self-pay treatment, similar to Saxenda for obesity. The specific cost per dose can vary, but both are generally expensive medications, making the total cost of treatment a significant factor for many patients.

Cost of Saxenda Treatment

Understanding the cost is crucial before starting Saxenda treatment, as it is typically not covered by health insurance when used for weight loss in Japan.

Saxenda Drug Price and Out-of-Pocket Expense

The price of Saxenda varies depending on the clinic or dispensing pharmacy. Since it is a self-pay treatment for obesity in Japan, clinics set their own prices. A single pen of Saxenda contains a total of 18 mg of liraglutide (3 ml of a 6 mg/ml solution). At the maximum dose of 3.0 mg per day, one pen lasts 6 days. At lower initial doses, it lasts longer.

The cost per pen typically ranges from approximately 20,000 to 35,000 Japanese Yen. Therefore, the monthly cost at the maintenance dose of 3.0 mg (requiring about 5 pens per month) could range from 100,000 to 175,000 Yen or more, plus consultation fees and other potential costs. This represents a significant ongoing expense.

Estimated Consultation and Examination Fees

In addition to the cost of the medication, you will also incur consultation fees and potentially examination fees (e.g., blood tests, body composition analysis) when visiting a clinic for diagnosis, prescription, and follow-up.

• Initial Consultation: Varies widely but can range from a few thousand Yen to over 10,000 Yen depending on the clinic and whether it’s a dedicated weight loss clinic or a general practice. Some clinics might offer initial consultations for free as part of a promotional package.
• Follow-up Consultations: Usually less expensive than the initial consultation, needed for monitoring progress, managing side effects, and renewing prescriptions.
• Examinations: Blood tests, ECG, etc., might be required before starting treatment to assess your health status and rule out contraindications. These add to the cost.

Total monthly costs, including medication and consultations, can therefore be substantial. Some clinics offer bundled packages or subscription services which might offer a slightly lower overall cost but require commitment.

Is Saxenda Covered by Insurance?

In Japan, Saxenda (Victoza) is covered by health insurance for the treatment of type 2 diabetes. However, Saxenda specifically for the treatment of obesity in individuals without diabetes is NOT covered by Japanese health insurance and is considered a self-pay treatment. This is a critical point for anyone considering Saxenda for weight loss purposes only. The full cost of the medication, consultation fees, and examinations must be borne by the patient. It is essential to confirm the exact cost structure with the clinic you choose before starting treatment.

Correct Way to Use Saxenda (Injection Method)

Saxenda is administered via a subcutaneous injection using a pre-filled pen. It is important to use the pen correctly to ensure you receive the proper dose and minimize discomfort or complications. You will be instructed by a healthcare professional on how to use the pen before your first injection.

Step-by-Step Guide to Using the Saxenda Pen

While specific instructions might vary slightly by pen design, the general steps are as follows:

• Check the Pen: Verify the pen is Saxenda, check the expiration date, and inspect the solution (should be clear and colorless).
• Attach a New Needle: Use a new, sterile needle for each injection. Remove the protective tab and screw or click the needle onto the pen. Remove the two needle caps (outer and inner).
• Check the Flow (Priming): Before the first injection with a new pen, or if you suspect the pen isn’t working correctly, check the flow. Turn the dose selector to the flow check symbol (usually two dots). Hold the pen with the needle pointing up and press and hold the dose button until the dose counter shows “0”. A drop of liquid should appear at the needle tip. If not, repeat the flow check up to 6 times. If still no drop, use a new pen.
• Select the Dose: Turn the dose selector to the required dose (e.g., 0.6 mg, 1.2 mg, 1.8 mg, 2.4 mg, or 3.0 mg). Ensure the dose counter shows the correct number. Do not select a dose larger than 3.0 mg.
• Inject the Dose: Choose an injection site. Insert the needle into the skin (subcutaneously) as instructed by your doctor. Press and hold the dose button down. Keep holding the button and watch the dose counter return to “0”. Continue to hold the needle under the skin and count slowly to 6 (or as instructed) to ensure the full dose is injected.
• Remove the Needle: Carefully pull the needle straight out of the skin.
• Dispose of the Needle: Safely remove the needle from the pen using the outer needle cap and dispose of it in a puncture-resistant sharps container immediately after use. Do not recap the needle with the inner cap.
• Store the Pen: Recap the pen body with the pen cap. Store the pen without the needle attached as recommended (refrigerated before opening, at room temperature or refrigerated after opening, for a specific duration).

Always refer to the pen’s instruction manual and follow your doctor’s guidance.

Recommended Injection Sites

Saxenda is injected subcutaneously (under the skin). The recommended injection sites are:

• Abdomen: The area around the waist, avoiding the belly button (stay at least 2 inches away). This is generally the preferred site for many.
• Thigh: The front of your thigh.
• Upper Arm: The back of your upper arm (if injecting yourself, this might be difficult).

Rotate injection sites regularly to avoid lipodystrophy (changes in fat tissue) or skin irritation. Do not inject into skin that is tender, bruised, scaly, or hard.

Gradual Dose Increase (Step-Up)

To minimize gastrointestinal side effects, Saxenda treatment typically starts at a low dose and is gradually increased over several weeks. A common step-up schedule is:

• Week 1: 0.6 mg once daily
• Week 2: 1.2 mg once daily
• Week 3: 1.8 mg once daily
• Week 4: 2.4 mg once daily
• Week 5 onwards: 3.0 mg once daily (maintenance dose)

Your doctor will advise you on the specific step-up schedule. If side effects are severe at any dose level, you might stay at that dose for a longer period before increasing, or your doctor might advise returning to a lower dose. Do not increase the dose if you cannot tolerate the current dose. The maximum dose is 3.0 mg per day.

Important Usage Precautions

• Daily Injection: Inject Saxenda once a day at any time of day, with or without food. Injecting at the same time each day might help remember the dose.
• Missed Dose: If you miss a dose, and it has been less than 12 hours since your scheduled time, take the missed dose as soon as possible. If it has been more than 12 hours, skip the missed dose and take your next dose at the regularly scheduled time the next day. Do not take a double dose to make up for a missed one.
• Storage: Store unused pens in the refrigerator (2°C to 8°C). After the first use, the pen can be stored for up to 30 days at room temperature (below 30°C) or in the refrigerator. Do not freeze Saxenda. Protect from light.
• Never Share Pens: Never share your Saxenda pen or needles with another person, even if the needle has been changed. This can transmit infections.
• Dispose of Sharps Safely: Always use a new needle for each injection and dispose of used needles in a designated sharps container.

Diet While on Saxenda Treatment and Foods to Avoid

Saxenda works best as part of a comprehensive weight management plan that includes a reduced-calorie diet and increased physical activity. While on Saxenda, paying attention to your diet can enhance its effectiveness and help manage potential side effects.

Dietary Tips to Enhance Treatment Effectiveness

• Calorie Deficit: Focus on consuming fewer calories than you burn. Saxenda helps reduce appetite, making it easier to stick to a lower-calorie diet.
• Balanced Nutrition: Choose nutrient-dense foods from all food groups: lean proteins, whole grains, fruits, vegetables, and healthy fats.
• Portion Control: Pay attention to serving sizes to manage calorie intake effectively.
• Regular Meal Times: Eating meals at consistent times can help regulate appetite and prevent excessive hunger that could lead to overeating.
• High-Fiber Foods: Fiber promotes satiety and aids digestion. Include plenty of vegetables, fruits, legumes, and whole grains.
• Lean Protein: Protein helps you feel full and preserves muscle mass during weight loss.

Are There Foods to Avoid While Using Saxenda?

There are no strict prohibitions on specific foods while using Saxenda. However, certain types of food might worsen the common gastrointestinal side effects like nausea and indigestion.

• High-Fat Foods: Greasy, fried, and fatty foods are generally slower to digest and can exacerbate nausea, bloating, and stomach discomfort. Since Saxenda also slows gastric emptying, a high-fat meal combined with Saxenda might lead to more pronounced symptoms.
• Very Sweet Foods: Some people find that very sugary foods can also contribute to nausea or discomfort.
• Large Meals: Overeating, especially after a period of reduced appetite, can trigger or worsen symptoms. Stick to smaller, moderate portions.
• Excessive Alcohol: Alcohol can irritate the stomach lining and may worsen nausea or other GI symptoms. It also adds empty calories which are counterproductive to weight loss.

Focusing on easily digestible, nutrient-rich foods, especially when first starting or increasing the dose, can help mitigate side effects.

Importance of Hydration

Staying adequately hydrated is very important while using Saxenda.

• Managing Side Effects: Nausea, vomiting, or diarrhea can lead to dehydration. Drinking plenty of water helps prevent dehydration and can sometimes alleviate nausea.
• General Health: Proper hydration supports overall metabolism and body functions, which are crucial during weight loss.
• Feeling Full: Sometimes thirst can be mistaken for hunger. Drinking water before meals can also contribute to feeling fuller.

Aim to drink water consistently throughout the day. Unsweetened tea or other non-caloric beverages are also acceptable.

What If You Don’t Feel Like You’re Losing Weight with Saxenda? Causes and Solutions

While Saxenda is an effective weight loss medication for many, some individuals may not achieve the desired results. If you feel like you’re not losing weight, it’s important to assess potential causes and discuss them with your doctor.

Dose Issues

• Dose Not High Enough: The target dose for weight loss with Saxenda is 3.0 mg daily. If you are still on a lower dose during the step-up phase, you may not experience the full weight loss effect yet. Ensure you are progressing towards the target dose as tolerated and as advised by your doctor.
• Not Reaching Target Dose: If you experience significant side effects at lower doses and cannot reach the 3.0 mg dose, your weight loss may be limited. Discuss tolerance and alternative strategies with your doctor.
• Inconsistent Dosing: Skipping doses or not injecting correctly can reduce the medication’s effectiveness.

Insufficient Combination with Diet and Exercise Therapy

Saxenda is an adjunct to, not a replacement for, lifestyle changes.

• Calorie Intake Still Too High: While Saxenda reduces appetite, it doesn’t eliminate it entirely. If you are still consuming more calories than you burn despite reduced appetite, you won’t lose weight. Review your diet and ensure you are maintaining a consistent calorie deficit.
• Lack of Physical Activity: Increasing physical activity burns calories, improves metabolism, and contributes significantly to weight loss and overall health. Ensure you are incorporating regular exercise into your routine.
• Poor Food Quality: Even if calorie intake is reduced, a diet lacking in nutrients or high in processed foods can hinder weight loss progress and overall well-being.

Possibility of Other Health Problems

Sometimes, underlying medical conditions or other medications can interfere with weight loss.

• Thyroid Problems: Hypothyroidism (underactive thyroid) can slow down metabolism and make weight loss difficult.
• Hormonal Imbalances: Conditions like Polycystic Ovary Syndrome (PCOS) or Cushing’s syndrome can affect weight.
• Other Medications: Some medications (e.g., certain antidepressants, corticosteroids, beta-blockers) can cause weight gain or make weight loss harder.
• Sleep Disorders: Insufficient or poor-quality sleep can affect hormones that regulate appetite and metabolism.
• High Stress Levels: Chronic stress can lead to hormonal changes that promote weight gain.

If you are struggling to lose weight despite using Saxenda correctly and making lifestyle changes, your doctor may want to investigate these or other potential factors. They can also evaluate if Saxenda is the most suitable medication for you or if an alternative treatment might be more effective.

Frequently Asked Questions About Saxenda Weight Loss (FAQ)

Here are answers to some common questions about using Saxenda for weight loss.

Do You Rebound If You Stop Saxenda?

There is a risk of regaining weight after stopping Saxenda, especially if the lifestyle changes (diet and exercise) that contributed to the weight loss are not maintained. Weight management is often a long-term effort. Saxenda helps facilitate weight loss and maintenance while you are using it. When you stop, the appetite-suppressing effects cease. Therefore, maintaining the healthy habits you developed during treatment is crucial to prevent regaining the lost weight. Your doctor can discuss strategies for weight maintenance after stopping Saxenda, which may include continued lifestyle focus or transitioning to other maintenance approaches.

Is There a Limit to the Treatment Period?

There is no strict, pre-defined maximum treatment period for Saxenda. In clinical trials, patients were studied for up to 56 weeks (about one year), showing sustained weight loss and maintenance. Long-term use beyond one year can be considered for patients who have achieved significant weight loss and benefit from continued treatment for weight maintenance, provided they tolerate the medication and there are no contraindications. The decision on how long to continue Saxenda should be made in consultation with your doctor based on your individual response, goals, and health status. Some individuals may use it long-term, while others might use it for a shorter period to achieve a goal and then focus on lifestyle maintenance.

Can It Be Used During Pregnancy and Breastfeeding?

No, Saxenda is contraindicated during pregnancy and breastfeeding. Weight loss during pregnancy is not recommended. If you are pregnant, planning to become pregnant, or breastfeeding, you should not use Saxenda. If you become pregnant while using Saxenda, you should stop the medication immediately and inform your doctor.

Where Can I Get Saxenda Prescribed?

Saxenda is a prescription medication. You can only get it from a licensed healthcare provider after a medical consultation. This typically involves visiting a clinic or hospital.

• Medical Clinics/Hospitals: Visit a doctor specializing in weight management, endocrinology, internal medicine, or even general practice. They will assess if Saxenda is appropriate for you based on your BMI, health conditions, medical history, and current medications.
• Online Clinics: In some regions, online medical consultation services offer prescriptions for weight loss medications like Saxenda. This can be a convenient option for those who have difficulty visiting a clinic in person. You will typically have a video or phone consultation with a doctor, during which you discuss your health and suitability for the medication. The medication is then shipped to your location. Ensure you use a reputable and licensed online medical service.

Regardless of whether you visit a clinic in person or use an online service, a proper medical consultation is mandatory to ensure the medication is safe and appropriate for you.

Other Injectable Weight Loss / Obesity Treatment Options

Besides Saxenda, other injectable medications are available or are emerging as options for weight management, primarily from the class of GLP-1 receptor agonists or related incretin mimetics.

Ozempic

As discussed earlier, Ozempic (semaglutide) is a GLP-1 receptor agonist primarily approved for type 2 diabetes but also leads to significant weight loss. It is administered weekly. A higher dose version specifically for obesity, Wegovy, has shown even greater weight loss efficacy than Saxenda in clinical trials and is approved for obesity in many countries, though its availability and insurance coverage vary.

Wegovy

Wegovy is semaglutide at a higher dose (up to 2.4 mg weekly) specifically indicated for chronic weight management. It has demonstrated superior weight loss results compared to placebo and Saxenda in studies. It works via the same GLP-1 mechanism as Ozempic and Saxenda but appears to have a stronger effect on appetite regulation at the higher dose.

Mounjaro

Mounjaro (tirzepatide) is a newer injectable medication that acts as a dual agonist for both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors. Originally approved for type 2 diabetes, clinical trials (SURMOUNT trials) have shown even greater weight loss compared to semaglutide. It is administered weekly. Its dual action mechanism is thought to contribute to its powerful effects on blood sugar control and weight reduction. Higher dose formulations for obesity under the brand name Zepbound are also being developed and approved.

Oral Medications (e.g., Xenical)

While injectables like GLP-1 agonists are prominent in newer weight loss treatments, oral medications are also available. Xenical (orlistat) is a lipase inhibitor that reduces the absorption of dietary fat in the intestines. It is available as a prescription or over-the-counter at a lower dose in some countries. Its weight loss effect is generally more modest compared to GLP-1 agonists, and it is often associated with gastrointestinal side effects like oily stools. Other oral medications targeting appetite or metabolism also exist but may have different mechanisms and side effect profiles.

The choice of medication depends on various factors, including the individual’s health status, co-existing conditions (like diabetes), weight loss goals, tolerance to side effects, cost, and preference for injection frequency. A doctor can help you determine the most suitable option.

How to Start Weight Loss with Saxenda

Beginning weight loss treatment with Saxenda involves a medical evaluation and the development of a personalized treatment plan with a healthcare professional.

Counseling and Diagnosis at a Clinic

The first step is to schedule a consultation with a doctor. This can be at a weight management clinic, an endocrinologist, or another physician experienced in treating obesity. During the consultation, the doctor will:

• Take a detailed medical history, including past weight loss attempts and any co-existing health conditions.
• Perform a physical examination.
• Measure your weight, height, and calculate your BMI.
• Discuss your weight loss goals and expectations.
• Assess if you meet the criteria for Saxenda treatment (BMI, comorbidities).
• Rule out any contraindications or conditions that might make Saxenda unsafe for you (e.g., history of pancreatitis, certain thyroid conditions, severe kidney/liver problems, pregnancy).
• Discuss potential side effects and how to manage them.

Creation of a Treatment Plan and Consent

If Saxenda is deemed appropriate and safe for you, the doctor will develop a personalized treatment plan. This plan will typically include:

• The starting dose of Saxenda and the schedule for dose escalation.
• Instructions on how to inject the medication correctly.
• Dietary recommendations (e.g., specific calorie targets or meal plans).
• Exercise recommendations.
• A schedule for follow-up appointments to monitor your progress, manage side effects, and adjust the treatment as needed.
• Discussion of the costs involved, as it is self-pay.

You will need to give informed consent before starting treatment, indicating that you understand the potential benefits, risks, and alternatives.

Starting Saxenda is a medical decision and should always be done under the supervision of a qualified healthcare provider. They will provide ongoing support throughout your weight loss journey. Online clinics offer a convenient alternative for initial consultation and prescription if they are licensed and reputable.

Conclusion: Consider Online Consultation to Purchase Saxenda Weight Loss

Saxenda is a promising injectable medication that can be an effective tool for weight loss when used in conjunction with diet and exercise. It works by mimicking the action of GLP-1, helping to reduce appetite and calorie intake, leading to significant weight loss for many individuals.

However, it is crucial to remember that Saxenda is a prescription medication and is not suitable for everyone. Potential side effects, though often mild, can occur, and serious side effects are rare possibilities that require vigilance. The cost of treatment can be substantial, as it is typically not covered by health insurance for weight loss purposes in Japan.

If you are considering Saxenda for weight loss, the most important step is to consult with a healthcare professional. They can assess your suitability for the medication, discuss the potential benefits and risks in your specific case, provide proper instructions on usage and dose titration, and guide you as part of a comprehensive weight management program.

For those who find it challenging to visit a clinic in person, online medical consultation services that are licensed and offer prescriptions for weight loss medications like Saxenda can be a convenient alternative. Regardless of the method, always ensure you are receiving treatment under the care of a qualified doctor.

Weight loss is a journey, and Saxenda can be a valuable ally, but it is most successful when combined with sustainable lifestyle changes and professional medical guidance.

Disclaimer: The information provided in this article is for general knowledge and informational purposes only, and does not constitute medical advice. It is essential to consult with a qualified healthcare professional for any health concerns or before making any decisions related to your health or treatment. Medication use, including Saxenda, should always be under the supervision and guidance of a licensed physician. Information regarding medication approval status, insurance coverage, and cost can change and may vary by region. Always confirm the latest information with your healthcare provider and relevant authorities.